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Effects of intubation timing in patients with COVID-19 throughout the four waves of the pandemic: a matched analysis.

Jordi RieraEnric BarbetaAdrián TormosRicard Mellado-ArtigasAdrián CeccatoAnna MotosLaia Fernández-BaratRicard FerrerDario García-GasullaOscar PeñuelasJosé Ángel LorenteRosario MenéndezOriol RocaAndrea PalomequeCarlos FerrandoJordi Solé-ViolánMariana NovoMaría Victoria BoadoLuis TamayoÁngel EstellaCristóbal GalbanJosep Trenado AlvarezArturo HuertaAna LozaLuciano AguileraJosé Luís García GarmendiaCarme BarberàVíctor GumucioLorenzo SociasNieves FrancoLuis Jorge ValdiviaPablo VidalVíctor SagredoÁngela Leonor Ruiz-GarcíaIgnacio Martínez VarelaJuan LópezJuan Carlos PozoMaite NietoJosé M GómezAaron BlandinoManuel ValledorElena Bustamante-MunguiraÁngel Sánchez-MirallesYhivian PeñascoJosé BarberánAlejandro UbedaRosario Amaya-VillarMaría Cruz MartínRuth JorgeJesús CaballeroJudith MarinJosé Manuel AñónFernando Suárez SipmannGuillermo MuñizÁlvaro Castellanos-OrtegaBerta Adell-SerranoMercedes CatalánAmalia Martínez de la GándaraPilar RicartCristina CarbajalesAlejandro RodríguezEmili DíazMari C de la TorreElena GallegoLuisa Cantón-BulnesNieves CarbonellJessica GonzálezDavid de Gonzalo-CalvoFerran BarbéAntoní Torresnull null
Published in: The European respiratory journal (2022)
In patients with COVID-19 requiring invasive mechanical ventilation, delayed intubation was associated with a higher risk of hospital mortality. The use of early intubation significantly decreased throughout the course of the pandemic. Benefits of such an approach occurred more notably in patients who had received high-flow nasal cannula.
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