Frontotemporal degeneration in amyotrophic lateral sclerosis (ALS): a longitudinal MRI one-year study.

Francesca TrojsiFederica Di NardoMattia SicilianoGiuseppina CaiazzoCinzia FemianoCarla PassanitiDario RicciardiAntonio RussoAlvino BiseccoSabrina EspositoMaria Rosaria MonsurròMario CirilloGabriella SantangeloFabrizio EspositoGioacchino Tedeschi

Published in: CNS spectrums (2020)

Our findings highlighted that progressive impairment of extramotor frontotemporal networks may precede the appearance of executive and language dysfunctions and GM changes in ALS. Functional connectivity changes in cognitive resting state networks might represent candidate radiological markers of disease progression.

Keyphrases

functional connectivity
resting state
amyotrophic lateral sclerosis
magnetic resonance imaging
multiple sclerosis
autism spectrum disorder
working memory
contrast enhanced