Long-term metabolic fate and mortality in obesity without metabolic syndrome.
Aki Juhani KäräjämäkiArto KorkiakoskiJanne HukkanenY Antero KesäniemiOlavi H UkkolaPublished in: Annals of medicine (2022)
In the present long-term follow-up study, the presence of MetS, but not obesity only, implies a greater risk of mortality and CVD. The risk of AF is increased only in subjects with both obesity and MetS. However, obesity without MetS tends to progress eventually to obesity with MetS. Key messagesThe presence of metabolic syndrome (MetS), but not obesity only, entails a greater risk of mortality and cardiovascular diseases.The risk of atrial fibrillation is increased only in subjects with both obesity and MetS.Obesity without MetS tends to progress eventually to obesity with MetS.
Keyphrases
- metabolic syndrome
- insulin resistance
- weight loss
- high fat diet induced
- type diabetes
- weight gain
- atrial fibrillation
- uric acid
- cardiovascular disease
- adipose tissue
- cardiovascular risk factors
- heart failure
- coronary artery disease
- body mass index
- percutaneous coronary intervention
- left ventricular
- mitral valve
- left atrial appendage