Angiotensin Receptor Blockers Are Not Just for Hypertension Anymore.
Juan M SaavedraPublished in: Physiology (Bethesda, Md.) (2021)
Beyond blood pressure control, angiotensin receptor blockers reduce common injury mechanisms, decreasing excessive inflammation and protecting endothelial and mitochondrial function, insulin sensitivity, the coagulation cascade, immune responses, cerebrovascular flow, and cognition, properties useful to treat inflammatory, age-related, neurodegenerative, and metabolic disorders of many organs including brain and lung.
Keyphrases
- angiotensin converting enzyme
- blood pressure
- angiotensin ii
- immune response
- oxidative stress
- white matter
- hypertensive patients
- heart rate
- resting state
- endothelial cells
- metabolic syndrome
- dendritic cells
- type diabetes
- physical activity
- body mass index
- functional connectivity
- multiple sclerosis
- brain injury
- blood glucose
- weight gain
- cerebral ischemia