AMPlify: attentive deep learning model for discovery of novel antimicrobial peptides effective against WHO priority pathogens.

Chenkai LiDarcy SutherlandS Austin HammondChen YangFigali TahoLauren BergmanSimon HoustonRené L WarrenTitus WongLinda M N HoangCaroline E CameronCaren C HelbingInanc Birol

Published in: BMC genomics (2022)

We demonstrate the utility of deep learning based tools like AMPlify in our fight against antibiotic resistance. We expect such tools to play a significant role in discovering novel candidates of peptide-based alternatives to classical antibiotics.

Keyphrases

deep learning
artificial intelligence
convolutional neural network
small molecule
machine learning
high throughput
gram negative
antimicrobial resistance