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Growth patterns of caudal fin rays are informed by both external signals from the regenerating organ and remembered identity autonomous to the local tissue.

Melody AutumnYinan HuJenny ZengSarah K McMenamin
Published in: bioRxiv : the preprint server for biology (2024)
Gene expression patterns during fin regeneration correspond with proximodistal location.Distal portions of rays transplanted to proximal regions retain positional identity that can influence their growth rate and length during regeneration.Location of ray bifurcations and length of segments along the proximodistal axis are determined by the regenerative environment.
Keyphrases
  • stem cells
  • gene expression
  • mesenchymal stem cells
  • dna methylation
  • cell therapy
  • minimally invasive
  • bone marrow