Breastfeeding Is Associated with Lower Likelihood of Helicobacter Pylori Colonization in Babies, Based on a Prospective USA Maternal-Infant Cohort.

Shailja C ShahLeonid TarassishinCaroline EiseleAlexa RendonAnketse DebebeKelly HawkinsChristen HillenbrandManasi AgrawalJoana TorresRichard M PeekJoanne StoneMarla DubinskyJean-Frederic ColombelInga PeterJianzhong Hu

Published in: Digestive diseases and sciences (2022)

Consistent with data from high H. pylori prevalence regions, our findings suggest dominant breastfeeding may protect against early H. pylori colonization. Downregulation of pro-inflammatory cytokines such as MMP-10 may be relevant in mediating this protection among breastfed babies, but more data are needed.

Keyphrases

helicobacter pylori
electronic health record
preterm infants
helicobacter pylori infection
big data
gestational age
risk factors
cell proliferation
birth weight
signaling pathway
machine learning