Genetic alteration and clonal evolution of primary glioblastoma into secondary gliosarcoma.

Jie LiYu-Hang ZhaoSu-Fang TianCheng-Shi XuYu-Xiang CaiKai LiYan-Bing ChengZe-Fen WangZhi-Qiang Li

Published in: CNS neuroscience & therapeutics (2021)

Secondary gliosarcoma components likely have a monoclonal origin, and the clone possessing mutations in NF1 and TP53 was likely the founding clone in this case of SGS.

Keyphrases

signaling pathway
lps induced
genome wide
pi k akt
nuclear factor
copy number
gene expression
immune response