Outcomes of protracted bacterial bronchitis in children: A 5-year prospective cohort study.
Tom J C RufflesJulie M MarchantIan B MastersStephanie T YerkovichDanielle F WurzelPeter G GibsonGreta BuschKatherine Joanne BainesJodie Louise SimpsonHeidi C Smith-VaughanSusan J PizzuttoHelen M BuntainGregory HodgeSandra HodgeJohn W UphamAnne Bernadette ChangPublished in: Respirology (Carlton, Vic.) (2020)
As a significant proportion of children with PBB have ongoing symptoms at 5 years, and outcomes include bronchiectasis and asthma, they should be carefully followed up clinically. Defining biomarkers, endotypes and mechanistic studies elucidating the different outcomes are now required.