Sex Differences in the Effect of Testosterone on Adipose Tissue Insulin Resistance From Overweight to Obese Adults.

Xiaohui LiJia LiuBiao ZhouYinhui LiZhengyu WuHua Meng Guang Wang

Published in: The Journal of clinical endocrinology and metabolism (2021)

Adipose-IR reflects the progressive deterioration in adipose tissue insulin sensitivity from overweight to obesity in both males and females. Males with class III obesity have more severe adipose-IR than similarly obese females. The sex difference is associated with testosterone, and low testosterone levels may contribute to more severe adipose-IR in obese males.

Keyphrases

adipose tissue
insulin resistance
weight loss
high fat diet
high fat diet induced
replacement therapy
metabolic syndrome
polycystic ovary syndrome
weight gain
early onset
physical activity
bariatric surgery
multiple sclerosis
type diabetes
glycemic control
body mass index
smoking cessation
drug induced