Radiofrequency ablation for cancer pain with inadequate opioid response.
Sebastiano MercadanteAlessandro SchiavelloPublished in: BMJ supportive & palliative care (2024)
Data on the use of radiofrequency (RT) to ablate a tumor mass-causing pain have not been reported. A male in his 50s, diagnosed with a pelvic relapse of rectal cancer, was admitted for pain from the left groin to the perineum. The principal findings of contrast-enhanced computed tomography (CT) revealed the presence in the pelvic area of large solid tissue infiltrating the internal obturator muscle and eroding the vertebral column of the acetabulum. Also involving the gluteal muscles.He was poorly responsive to multiple opioids. He was treated with RT under CT guidance to ablate the pelvic mass. Pain relief was immediate as it was possible to reduce methadone doses since the afternoon of the operation day. Very selected patients who are not responsive to optimisation of opioid therapy, could be candidates to RF of the tumor mass, that may offer an efficient method to provide fast pain relief and allowing opioid dose reduction.
Keyphrases
- chronic pain
- pain management
- contrast enhanced
- computed tomography
- rectal cancer
- magnetic resonance imaging
- neuropathic pain
- dual energy
- positron emission tomography
- radiofrequency ablation
- diffusion weighted
- magnetic resonance
- skeletal muscle
- squamous cell carcinoma
- diffusion weighted imaging
- single cell
- deep learning
- postmenopausal women
- lymph node metastasis
- electronic health record
- drug delivery
- body composition
- bone marrow
- mesenchymal stem cells
- mass spectrometry
- solid phase extraction
- ultrasound guided