The anti-scarring effect of corneal stromal stem cell therapy is mediated by transforming growth factor β3.
Lin WengJames L FunderburghIrona KhandakerMoira L GearyTianbing YangRohan BasuMartha L FunderburghYiqin DuGary Hin-Fai YamPublished in: Eye and vision (London, England) (2020)
This study has demonstrated that the corneal regenerative effect of hCSSC is mediated by TGFβ3, inducing a scar-free tissue response.