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The anti-scarring effect of corneal stromal stem cell therapy is mediated by transforming growth factor β3.

Lin WengJames L FunderburghIrona KhandakerMoira L GearyTianbing YangRohan BasuMartha L FunderburghYiqin DuGary Hin-Fai Yam
Published in: Eye and vision (London, England) (2020)
This study has demonstrated that the corneal regenerative effect of hCSSC is mediated by TGFβ3, inducing a scar-free tissue response.
Keyphrases
  • cell therapy
  • transforming growth factor
  • epithelial mesenchymal transition
  • stem cells
  • wound healing
  • mesenchymal stem cells
  • optical coherence tomography
  • bone marrow
  • signaling pathway
  • tissue engineering