Marginal Structural Models to Assess Delays in Second-Line HIV Treatment Initiation in South Africa.
Julia K RohrPrudence IveC Robert HorsburghRebecca BerhanuKate ShearerMhairi MaskewLawrence LongIan SanneJean BassettOsman EbrahimMatthew P FoxPublished in: PloS one (2016)
Even small delays in switch to second-line ART were associated with increased death and second-line failure among patients with low CD4 counts on first-line. There is opportunity for healthcare providers to switch patients to second-line more quickly.