Effects of the herbal preparation STW 5-II on in vitro muscle activity in the guinea pig stomach.
Michael SchemannMartina LandmannO KelberRamy M AmmarDagmar KruegerK MichelPublished in: Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society (2020)
STW 5-II had a region-specific effect and relaxed the proximal stomach but increased the contractility in the antrum. It was as effective as STW 5 which may explain its comparable clinical effects in treating functional dyspepsia. Impaired accommodation may be normalized through relaxation of the fundus, while the motility-promoting effects leading to an increase in antral motility may activate the gastric pump.