The current state, challenges, and future directions of deep brain stimulation for obsessive compulsive disorder.

To continue increasing efficacy of DBS for OCD, we must further explore optimal DBS response across clinical profiles and neuropsychiatric domains of OCD as well as how interventions targeting multiple points in an aberrant circuit, multiple aberrant circuits, or a connectivity hub impacts clinical response. Additionally, biomarkers would be invaluable in programming adjustments and creating a closed-loop paradigm to address symptom fluctuation in daily life.