Personalised circulating tumour DNA assay with large-scale mutation coverage for sensitive minimal residual disease detection in colorectal cancer.
Seung Bum RyooSunghoon HeoYoojoo LimWookjae LeeSu Han ChoJongseong AhnJun-Kyu KangSu Yeon KimHwang-Phill KimDuhee BangSung-Bum KangChang Sik YuSeong Taek OhJi-Won ParkSeung-Yong JeongYoung-Joon KimKyu Joo ParkSae-Won HanTae-You KimPublished in: British journal of cancer (2023)
Tumour-informed, hybrid-capture-based ctDNA assay monitoring a large number of patient-specific mutations is a sensitive strategy for MRD detection to predict recurrence in CRC.