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Phenotypic characterization and comparative transcriptomics of evolved Saccharomyces cerevisiae strains with improved tolerance to lignocellulosic derived inhibitors.

Olivia A ThompsonGary M HawkinsSteven W GorsichJoy Doran-Peterson
Published in: Biotechnology for biofuels (2016)
Multiple potentially novel genetic targets have been discovered for understanding stress tolerance through the characterization of our evolved strains. This study specifically examines the synergistic effects of multiple inhibitors and identified targets will guide future studies in remediating effects of inhibitors and further development of robust yeast strains for multiple industrial applications.
Keyphrases
  • saccharomyces cerevisiae
  • escherichia coli
  • single cell
  • heavy metals
  • wastewater treatment
  • cancer therapy