Effect of sustained postnatal systemic inflammation on hippocampal volume and function in mice.
Shadi N MalaebJonathan M DavisIlka M PinzJennifer L NewmanOlaf DammannMaribel RiosPublished in: Pediatric research (2014)
Systemic inflammation sustained during the postnatal period contributes to reduced hippocampal volume and deficits in hippocampus-dependent working memory. These findings support the novel and emerging concept that sustained systemic inflammation contributes to neurodevelopmental impairment among preterm infants.