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Inverse relationship between IL-6 and sodium levels in patients with COVID-19 and other respiratory tract infections: data from the COVIVA study.

Cihan AtilaSophie MonneratRoland BingisserMartin SiegemundMaurin LampartMarco RueeggNúria ZellwegerStefan OsswaldKatharina RentschMirjam Christ-CrainRaphael Twerenbold
Published in: Endocrine connections (2022)
IL-6 levels were inversely correlated with plasma sodium levels, with a stronger correlation in COVID-19 compared to bacterial and other viral infections. IL-6 might stimulate AVP secretion and lead to higher rates of hyponatremia due to the SIAD in these patients.
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