Integration of omics studies indicates that species-dependent molecular mechanisms govern male fertility.

Yoo-Jin ParkWon-Ki PangMyung-Geol Pang

Published in: Journal of animal science and biotechnology (2023)

Overall, this approach demonstrated that distinct molecular pathways drive sperm fertility in mammals in a species-dependent manner. Moreover, we anticipate that searching for species-specific signaling pathways may aid in the discovery of fertility-related biomarkers within large omics datasets.

Keyphrases

single cell
signaling pathway
childhood cancer
small molecule
genetic diversity
high throughput
rna seq
pi k akt
single molecule
induced apoptosis