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Metal-free visible-light-enabled vicinal trifluoromethyl dithiolation of unactivated alkenes.

Xiaojuan LiQiang ZhangWeigang ZhangJinzhu MaYi WangYi Pan
Published in: Beilstein journal of organic chemistry (2021)
The difunctionalization of alkenes involving a trifluoromethylthio group (SCF3) for the conversion of versatile and readily available olefins into structurally more complex molecules has been successfully studied. However, the disproportionate dithiolation of alkenes is unknown. Herein, a transition-metal-free protocol is presented for the vicinal trifluoromethylthio-thiolation of unactivated alkenes via a radical process under mild conditions with a broad substrate scope and excellent tolerance.
Keyphrases
  • visible light
  • amino acid
  • solid state