Keratinocytes stimulate MAIT cells to produce granzyme B via MR1 and cytokines in oral lichen planus.

Qin JiangFang WangGang Zhou

Published in: Oral diseases (2024)

Keratinocytes were capable to activate MAIT cells via MR1 and cytokines in OLP, and granzyme B produced by activated MAIT cells intensified keratinocyte apoptosis, engaging in the pathogenesis of OLP.

Keyphrases

cell cycle arrest
induced apoptosis
cell death
endoplasmic reticulum stress
magnetic resonance
pi k akt
signaling pathway
computed tomography
contrast enhanced