Renal Proximal Tubule Cell-specific Megalin Deletion Does Not Affect Atherosclerosis But Induces Tubulointerstitial Nephritis in Mice Fed Western Diet.
Naofumi AmiokaMichael K FranklinMasayoshi KukidaHisashi Sawada (澤田悠)Jessica J MoorleghenDeborah A HowattYuriko KatsumataAdam E MullickMotoko YanagitaMichelle M Martinez-IrizarryRuben M SandovalKenneth W DunnAlan DaughertyHong S Lu (吕红)Published in: bioRxiv : the preprint server for biology (2024)
PTC-specific megalin deletion does not affect atherosclerosis, but leads to tubulointerstitial nephritis in mice fed Western diet, with severe pathologies in male mice.