Second-Generation Cephalosporins-Associated Drug-Induced Liver Disease: A Study in VigiBase with a Focus on the Elderly.
Mariana SiposAndreea FarcasDaniel-Corneliu LeucutaCamelia BucșaMadalina HurubaCristina Ionela MogoșanPublished in: Pharmaceuticals (Basel, Switzerland) (2021)
Hepatobiliary ADRs were reported for 2nd generation cephalosporins, with over 50% of cases in adults, without gender differences. Cholestatic hepatitis was predominately reported in the elderly and this category was more prone to specific hepatic reactions.