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Second-Generation Cephalosporins-Associated Drug-Induced Liver Disease: A Study in VigiBase with a Focus on the Elderly.

Mariana SiposAndreea FarcasDaniel-Corneliu LeucutaCamelia BucșaMadalina HurubaCristina Ionela Mogoșan
Published in: Pharmaceuticals (Basel, Switzerland) (2021)
Hepatobiliary ADRs were reported for 2nd generation cephalosporins, with over 50% of cases in adults, without gender differences. Cholestatic hepatitis was predominately reported in the elderly and this category was more prone to specific hepatic reactions.
Keyphrases
  • drug induced
  • liver injury
  • middle aged
  • community dwelling
  • adverse drug
  • liver fibrosis