Intratumoral infiltrating lymphocytes correlate with improved survival in colorectal cancer patients: Independent of oncogenetic features.
Ehsan Nazemalhosseini MojaradSomayeh MohammadpourAmir Torshizi EsafahaniEhsan GharibPegah LarkiAfshin MoradiMohammad Amin PorhoseingholiHamid Asadzade AghdaeiPeter J K KuppenMohammad Reza ZaliPublished in: Journal of cellular physiology (2018)
These results suggest that intratumor cell-infiltrating CD8- T lymphocytes as an independent prognostic factor that have an antitumor activity as judged by their favorable effect on patients' survival and could potentially be exploited in the treatment of CRC.