Headgroup engineering in mechanosensitive membrane probes.

Saeideh SoleimanpourAdai ColomEmmanuel DeriveryMarcos Gonzalez-GaitanAurelien RouxNaomi SakaiStefan Matile

Published in: Chemical communications (Cambridge, England) (2018)

Systematic headgroup engineering yields planarizable push-pull flipper probes that are ready for use in biology - stable, accessible, modifiable -, and affords non-trivial insights into chalcogen-bond mediated mechanophore degradation and fluorescence enhancement.

Keyphrases

single molecule
small molecule
living cells
fluorescence imaging
fluorescent probe
energy transfer
photodynamic therapy
transition metal