Treatment of Neuropsychiatric Symptoms in Parkinson's Disease With Botulinum Toxin A: A 12 week Randomized, Double-Blind, Placebo-Controlled Trial.

Xiaofeng ZhuMing WeiLijun WangQiang TongXiu YangQiu Han

Published in: Journal of geriatric psychiatry and neurology (2024)

PD patients commonly experience multiple neuropsychiatric symptoms, and BoNT/A has demonstrated efficacy in alleviating these symptoms. Specifically, BoNT/A was found to effectively alleviate somatization, tension, anxiety, depression, and sensitivity in PD patients.

Keyphrases

double blind
end stage renal disease
placebo controlled
ejection fraction
newly diagnosed
chronic kidney disease
sleep quality
botulinum toxin
peritoneal dialysis
prognostic factors
depressive symptoms
study protocol
phase iii
patient reported