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Transplantation of tauroursodeoxycholic acid-inducing M2-phenotype macrophages promotes an anti-neuroinflammatory effect and functional recovery after spinal cord injury in rats.

Gong Ho HanSeong Jun KimWan-Kyu KoDaye LeeIn-Bo HanSeung Hun SheenJe Beom HongSeil Sohn
Published in: Cell proliferation (2021)
This study demonstrates that the transplantation of TUDCA-induced M2 macrophages promotes an anti-neuroinflammatory effect and motor function recovery in SCI. Therefore, we suggest that the transplantation of TUDCA-induced M2 macrophages represents a possible alternative cell therapy for SCI.
Keyphrases
  • spinal cord injury
  • spinal cord
  • cell therapy
  • high glucose
  • diabetic rats
  • drug induced
  • neuropathic pain
  • oxidative stress
  • bone marrow