Adult hair follicles keep oncogenic growth in check.

Published in: The Journal of cell biology (2019)

Recent research shows that potentially cancerous, somatic mutations can reside in normal cells. Pineda et al. (2019. J. Cell Biol. https://doi.org/10.1083/jcb.201907178) report on a unique management technique by hair follicle stem cells to evade tumorigenesis.

Keyphrases

stem cells
induced apoptosis
cell therapy
cell cycle arrest
single cell
transcription factor
endoplasmic reticulum stress
copy number
signaling pathway
oxidative stress
gene expression
bone marrow
pi k akt