Cylindroma of the breast with CYLD gene mutation: a case report and review of the literature.
Vanessa Escher-MichligTatjana VlajnicLuca RomaMattia MarinucciSalvatore PiscuoglioMatthias MatterMartin HaugWalter P WeberSimone MuenstPublished in: Molecular biology reports (2023)
Careful evaluation of morphological features such as mitotic figures and cellular atypia is crucial in the diagnostic work-up of triple-negative breast lesions. It is important to keep cylindroma in mind as a pitfall and possible differential diagnosis for the solid-basaloid variant of adenoid cystic carcinoma. Molecular detection of CYLD gene mutation is helpful in cases with ambiguous histology. With this case report, we aim to contribute to a better understanding of mammary cylindroma and facilitate the diagnosis of this rare entity.
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