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Validation of the Modified Checklist for Autism in Toddlers, Revised with Follow-up in a Population Sample of 30-Month-Old Children in Iceland: A Prospective Approach.

Sigridur Loa JonsdottirEvald SaemundsenBrynjolfur Gauti JonssonVilhjalmur Rafnsson
Published in: Journal of autism and developmental disorders (2021)
The Modified Checklist for Autism in Toddlers, Revised with Follow-up was validated on a population sample in Reykjavik, Iceland. The participants (N = 1585) were screened in well-child care at age 30 months and followed up for at least 2 years to identify autism cases. The sensitivity, specificity, positive and negative predictive values were 0.62, 0.99, 0.72, and 0.99, respectively. True-positive children were diagnosed 10 months earlier than false-negative children. Autism symptom severity and the proportions of children with verbal and performance IQs/DQs < 70 were similar between groups. Although the sensitivity was suboptimal, the screening contributed to lowering the age at diagnosis for many children. Adding autism-specific screening to the well-child care program should be considered.
Keyphrases
  • autism spectrum disorder
  • young adults
  • intellectual disability
  • healthcare
  • palliative care
  • mental health
  • quality improvement
  • chronic pain
  • health insurance