Trehalose alleviates the phenotype of Machado-Joseph disease mouse models.
Magda M SantanaSusana PaixãoJanete Cunha-SantosTeresa Pereira SilvaAllyson Trevino-GarciaLaetitia S GasparClévio NóbregaRui Jorge NobreCláudia CavadasHagar GreifLuis Pereira de AlmeidaPublished in: Journal of translational medicine (2020)
The present study suggests trehalose as a safety pharmacological strategy to counteract MJD-associated behavioural and neuropathological impairments.
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