High-sensitive troponinT, interleukin-8, and interleukin-6 link with post-surgery risk in infant heart surgery.

Elin M ThorlaciusJuho Keski-NisulaMaria VistnesTiina OjalaMattias MolinMats SynnergrenBirgitta S Romlin Sven-Erik RickstenHåkan WåhlanderAlbert Gyllencreutz Castellheim

Published in: Acta anaesthesiologica Scandinavica (2024)

The peak biomarker concentrations and CPB-time strongly predicted AKI2-3, with IL-6 and IL-8 emerging as strongest predictors. Furthermore, our findings suggest that measuring hs-cTnT and IL-8 just 2 h post-CPB-weaning may assist in identifying infants suitable for early extubation and highlight those at risk of prolonged ventilation.

Keyphrases

minimally invasive
mechanical ventilation
coronary artery bypass
acute kidney injury
heart failure
surgical site infection
cardiac surgery
respiratory failure
atrial fibrillation
acute respiratory distress syndrome
coronary artery disease
extracorporeal membrane oxygenation