Innate and Acquired Quinine-Resistant Alcohol, but not Saccharin, Drinking in Crossed High-Alcohol-Preferring Mice.

Christa A HouckClaire R CarronLauren A MillieNicholas J Grahame

Published in: Alcoholism, clinical and experimental research (2019)

These data suggest that an alcohol drinking history induces maladaptive behaviors, such as drinking in spite of negative consequences, a pattern not seen with saccharin. Furthermore, a strong genetic predisposition to drink may promote an innate aversion resistance compared with commonly used inbred strains.

Keyphrases

alcohol consumption
immune response
escherichia coli
electronic health record
type diabetes
genome wide
high fat diet induced
big data
gene expression
metabolic syndrome
insulin resistance
artificial intelligence
data analysis