The Prognostic Impact of KRAS Mutation in Patients Having Curative Resection of Synchronous Colorectal Liver Metastases.

Paolo GoffredoAlan F UtriaAnna C BeckYun Shin ChunJames R HoweRonald J WeigelJean-Nicolas VautheyImran Hassan

Published in: Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract (2018)

m-KRAS is associated with worse OS in patients presenting with colorectal cancer and liver metastases undergoing resection of the primary tumor and metastatic disease. Right-sided lesions and African-American race were associated with m-KRAS. However, while right-sided remained an independent prognostic factor for OS, race did not.

Keyphrases

liver metastases
prognostic factors
african american
wild type
end stage renal disease
small cell lung cancer
squamous cell carcinoma
newly diagnosed
ejection fraction
peritoneal dialysis