Long access to cocaine self-administration dysregulates the glutamate synapse in the nucleus accumbens core of serotonin transporter knockout rats.

Lucia Caffino Francesca Mottarlini Giorgia TargaMichel M M VerheijJudith Regina Homberg Fabio Fumagalli

Published in: British journal of pharmacology (2021)

Our findings reveal that SERT deletion may sensitize the glutamatergic synapses of the nucleus accumbens core to the long access but not short access, intake of cocaine.

Keyphrases

genome wide
single cell
prefrontal cortex
weight gain
gene expression
body mass index