Comparison of inexperienced operators and experts in γH2A.X and 53BP1 foci assay for high-throughput biodosimetry approaches in a mass casualty incident.

Martin BucherLukas DuchrowDavid EndesfelderUte RoesslerMaria Gomolka

Published in: International journal of radiation biology (2020)

In case of a large-scale radiation event, inexperienced staff is useful to support laboratories in slide preparation for semi-automatic foci counting as well as γH2A.X and 53BP1 manual foci scoring for triage-mode biodosimetry. Slides can be clearly classified in the non-, low- or high-exposed category.

Keyphrases

high throughput
emergency department
cardiovascular disease
single cell
deep learning
type diabetes
radiation therapy
molecularly imprinted
mass spectrometry
high resolution
solid phase extraction