Metformin Reduces Renal Uptake of Radiotracers and Protects Kidneys from Radiation-Induced Damage.
Chiyi XiongDengke YinJunjie LiQian HuangMurali K RavooriVikas KundraHua ZhuZhi YangYang LuChun Li
Published in: Molecular pharmaceutics (2019)
Metformin inhibits kidney uptake of peptidyl radiotracers, protecting the kidney from nephrotoxicity. Further studies are needed to elucidate the mechanisms of these finding and to optimize mitigation of radiation-induced damage to kidney in PRRT.