Simulation of long-term impact of intravitreal anti-VEGF therapy on patients with severe non-proliferative diabetic retinopathy.

Quan Dong NguyenAndrew A MoshfeghiJennifer I LimEkaterina PonomarevaAnkita ChauhanRohini RaoSteven Sherman

Published in: BMJ open ophthalmology (2023)

The model suggests treating severe NPDR early with anti-VEGF therapy, rather than delaying treatment until PDR develops, could significantly reduce PDR incidence over 5 years and sustained blindness over 10 years.

Keyphrases

diabetic retinopathy
vascular endothelial growth factor
optical coherence tomography
endothelial cells
risk factors
drug induced