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Circulating Tumor DNA Dynamics Fail to Predict Efficacy of Poly(ADP-ribose) Polymerase/VEGFR Inhibition in Patients With Heavily Pretreated Advanced Solid Tumors.

Yiduo HuAzeet NarayanYunshan XuJulia WolfeDennis VuThi TrinhChaitanya KantakSusan Percy IvyJoseph Paul EderYanhong DengPatricia LoRussoJoseph W KimAbhijit A Patel
Published in: JCO precision oncology (2024)
ctDNA levels or dynamics did not correlate with radiographic response or survival outcomes in patients with advanced metastatic malignancies treated with olaparib and cediranib.
Keyphrases
  • circulating tumor
  • cell free
  • circulating tumor cells
  • squamous cell carcinoma
  • small cell lung cancer
  • vascular endothelial growth factor
  • structural basis