Neuromelanin imaging analyses of the substantia nigra in patients with Machado-Joseph disease.

Yasuhiro NakataAtsuko SakamotoAkihiro Kawata

Published in: Neuroradiology (2020)

Neuromelanin in the SN may decrease at the early stage of the disease and continue to decrease over time with the disease duration in MJD/SCA3 patients. The NRC may be a useful biological index for monitoring MJD/SCA3.

Keyphrases

early stage
end stage renal disease
newly diagnosed
high resolution
ejection fraction
chronic kidney disease
squamous cell carcinoma
prognostic factors
photodynamic therapy