Prevalence of CYP2C19 polymorphism in Bogotá, Colombia: The first report of allele *17.

Azucena Arévalo-Galvis William A Otero-ReginoGloria N Ovalle-CelisEliana Rocío RodríguezAlba A Trespalacios-Rangel

Published in: PloS one (2021)

The population studied consisted mainly of extensive and ultrarapid PPI metabolizers. These findings show that it is necessary to increase PPI doses in this group of subjects or to use PPIs that are not metabolized by CYP2C19 (rabeprazole). This is the first Colombian work to identify ultrarapid metabolizers.

Keyphrases

protein protein
risk factors
small molecule