Identification of Novel Genetic Risk Factors for Focal Segmental Glomerulosclerosis in Children: Results From the Chronic Kidney Disease in Children (CKiD) Cohort.

Axelle DurandCheryl A WinklerNicolas VinceVenceslas DouillardEstelle GeffardElizabeth Binns-RoemerDerek K NgPierre-Antoine GourraudKimberley ReidyBradley WaradySusan FurthJeffrey B KoppFrederick J KaskelSophie Limou

Published in: American journal of kidney diseases : the official journal of the National Kidney Foundation (2023)

Our genetic study has identified functionally relevant risk factors and the importance of immune regulation for pediatric primary FSGS, which contributes to a better description of its molecular pathophysiological mechanisms.

Keyphrases

chronic kidney disease
risk factors
young adults
genome wide
end stage renal disease
copy number