Antibody response against Pseudomonas aeruginosa and its relationship with immune mediators in the upper and lower airways of cystic fibrosis patients.
Renan Marrichi MauchJulia HentschelKasper AanaesAnton BaruchaMarcos T Nolasco da SilvaCarlos E LevyNiels HøibyJochen G MainzPublished in: Pediatric pulmonology (2020)
The anti-P. aeruginosa IgA response was more prominent in CF patients' UAW, indicating a lower degree of inflammatory responses. Proteases may play a role in the anti-P. aeruginosa humoral response in the upper and LAW, and anti-P. aeruginosa IgG may be involved in the crosstalk between upper and lower airways in cystic fibrosis patients.
Keyphrases
- cystic fibrosis
- pseudomonas aeruginosa
- end stage renal disease
- ejection fraction
- chronic kidney disease
- newly diagnosed
- peritoneal dialysis
- immune response
- prognostic factors
- patient reported outcomes
- escherichia coli
- chronic obstructive pulmonary disease
- multidrug resistant
- air pollution
- biofilm formation
- acinetobacter baumannii