Lymphovascular Invasion Is Associated with Lymph Node Involvement in Small Appendiceal Neuroendocrine Tumors.
Andrew M BlakelyMustafa RaoofPhilip H G ItuarteYuman FongGagandeep SinghByrne LeePublished in: Annals of surgical oncology (2019)
Node involvement is associated with worse overall survival in appendiceal NETs. The presence of LVI was strongly associated with lymph node involvement. An appendectomy specimen showing LVI should prompt strong consideration of colectomy with regional lymphadenectomy even for small, typical appendiceal NETs.