Impact of high on-treatment platelet reactivity on outcomes following PCI in patients on hemodialysis: An ADAPT-DES substudy.
Geoffrey A RubinAjay J KirtaneShmuel ChenBjörn RedforsGiora WeiszUsman BaberYiran ZhangThomas D StuckeyBernhard WitzenbichlerMichael J RinaldiFranz-Josef NeumannD Christopher MetzgerTimothy D HenryDavid A CoxPeter L DuffyBruce R BrodieErnest L MazzaferriRoxana MehranZiad A AliOri Ben-YehudaGregg W StonePublished in: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions (2019)
Nearly two-thirds of patients on HD exhibited HPR on clopidogrel, and both HD and HPR were independently associated with 2-year adverse outcomes after DES implantation. However, the deleterious impact of HD on clinical outcomes was present in both patients with and without HPR.
Keyphrases
- end stage renal disease
- chronic kidney disease
- peritoneal dialysis
- ejection fraction
- newly diagnosed
- prognostic factors
- coronary artery disease
- percutaneous coronary intervention
- acute myocardial infarction
- patient reported outcomes
- left ventricular
- patient reported
- antiplatelet therapy
- st elevation myocardial infarction
- coronary artery bypass grafting
- st segment elevation myocardial infarction