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Comparison of cytotoxic and apoptosis-inducing effects of MTA, propolis, and propolis-MTA on immature dental pulp stem cells.

B Nazemi SalmanM KalantariM Mohebbi RadEhsan Saburi
Published in: European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry (2023)
Propolis-MTA showed higher biocompatibility than MTA. Addition of propolis to MTA improved cell proliferation in the first 24-h. Also, the cytotoxicity of propolis was lower than other materials in the first 24-h. Thus, propolis may serve as a promising pulp capping agent given that its other properties are approved.
Keyphrases
  • stem cells
  • cell proliferation
  • oxidative stress
  • endoplasmic reticulum stress
  • bone marrow