The association between reasons for first using cannabis, later pattern of use, and risk of first-episode psychosis: the EU-GEI case-control study.
Edoardo SpinazzolaDiego QuattroneVictoria RodriguezGiulia TrottaLuis AlamedaGiada TripoliCharlotte Gayer-AndersonTom P FreemanEmma C JohnsonHannah E JongsmaSimona StiloCaterina La CasciaLaura FerraroDaniele La BarberaAntonio LasalviaSarah TosatoIlaria TarriconeGiuseppe D'AndreaMichela GalatoloAndrea TortelliIlaria TagliabueMarco TurcoMaurizio PompiliJean-Paul SeltenLieuwe de HaanPaulo Rossi MenezesCristina M Del BenJose Luis SantosManuel ArrojoJulio BobesJulio SanjuánMiguel BernardoCelso ArangoJames B KirkbridePeter B JonesMichael O'DonovanBart P RuttenJim Van OsCraig MorganPak C ShamIsabelle Austin-ZimmermanZhikun LiEvangelos Vassosnull nullRobin M MurrayMarta Di FortiPublished in: Psychological medicine (2023)
Both FEPp and controls usually started using cannabis with their friends, but more patients than controls had begun to use 'to feel better'. People who reported their reason for first using cannabis to 'feel better' were more likely to progress to heavy use and develop a psychotic disorder than those reporting 'because of friends'.