Detection of tumor-specific DNA methylation markers in the blood of patients with pituitary neuroendocrine tumors.
Grayson A HerrgottKaram P AsmaroMichael WellsThais S SabedotTathiane M MaltaMaritza S MosellaKevin NelsonLisa ScarpaceJill S Barnholtz-SloanAndrew E SloanWarren R SelmanAna C deCarvalhoLaila M PoissonAbir MukherjeeAdam M RobinIan Y LeeJames SnyderTobias WalbertMark RosenblumTom MikkelsenArti BhanJohn R CraigSteven KalkanisJack RockHoutan NoushmehrAna Valeria CastroPublished in: Neuro-oncology (2022)
Our results underpin the potential application of methylation-based LB profiling as a noninvasive approach to identify clinically relevant epigenetic markers to diagnose and potentially impact the prognostication and management of patients with PitNETs.