MicroRNA-326-3p ameliorates high glucose and ox-LDL-IC- induced fibrotic injury in renal mesangial cells by targeting FcγRIII.

Yiting WangRui ZhangJunlin ZhangFang Liu

Published in: Nephrology (Carlton, Vic.) (2019)

FcγRIII was identified as a target gene of miR-326-3p. MiR-326-3p/FcγRIII/TGF-β/Smad signaling pathway was investigated to be involved in the pathophysiology of renal fibrosis of DKD.

Keyphrases

high glucose
endothelial cells
signaling pathway
transforming growth factor
epithelial mesenchymal transition
systemic sclerosis
genome wide
idiopathic pulmonary fibrosis
pi k akt
low density lipoprotein
atomic force microscopy
gene expression
stress induced
single molecule